Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Total minimum lease payments Lessee, Operating Lease, Liability, to be Paid Foreign Currency Translation Foreign Currency Transactions and Translations Policy [Policy Text Block] Subject to FDA approval of Zimura in GA Tranche Five [Member] Tranche Five 2022 Term Loan Facility, gross (amount drawn) Long-Term Debt, Gross Entity Address, Postal Zip Code Entity Address, Postal Zip Code Prepayment penalty thereafter Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs Occurs On Or After The Second Anniversary And Prior To The Third Anniversary Of The Closing Date Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs Occurs On Or After The Second Anniversary And Prior To The Third Anniversary Of The Closing Date Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Deferred: Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Investments, fair value disclosure Investments, Fair Value Disclosure Debt Instrument [Axis] Debt Instrument [Axis] Property and equipment, gross Property, Plant and Equipment, Gross Prepayment penalty second year Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs On Or After The First Anniversary And Prior To The Second Anniversary Of The Closing Date Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs On Or After The First Anniversary And Prior To The Second Anniversary Of The Closing Date Right-of-use asset Deferred Tax Liabilities, Right-Of-Use Asset Deferred Tax Liabilities, Right-Of-Use Asset Aggregate principal amount (up to) Line of Credit Facility, Maximum Borrowing Capacity Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Depreciation Deferred Tax Liabilities, Property, Plant and Equipment Supplemental disclosure of cash paid Supplemental Disclosure of Cash Paid [Abstract] Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Additional paid-in capital Additional Paid in Capital Investing Activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] On Closing Date Tranche One [Member] Tranche One Financial Instrument [Domain] Financial Instruments [Domain] Basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Statistical Measurement [Domain] Statistical Measurement [Domain] Depreciation Depreciation expense Depreciation Accrued research and development expenses Accrued Research and Development Sum of the carrying values as of the balance sheet date of obligations incurred through that date and due within one year (or the operating cycle, if longer) for research and development related activities. 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Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Contingent Consideration by Type [Axis] Contingent Consideration by Type [Axis] Total antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Subsequent Event Type [Axis] Subsequent Event Type [Axis] Contingent Development And Regulatory Milestone Payments Contingent Development And Regulatory Milestone Payments [Member] Contingent Development And Regulatory Milestone Payments Summary of the Stock Options Outstanding and Exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block] Equity Component [Domain] Equity Component [Domain] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Basic and diluted net income (loss) per common share calculation: Earnings Per Share 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Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Loan and Security Agreement Debt Disclosure [Text Block] Issuance of common stock under the exercise of pre-funded warrants Stock Issued During Period, Value, Conversion of Units Asset Acquisition [Axis] Asset Acquisition [Axis] Product and Service [Domain] Product and Service [Domain] Operating Activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Entity Shell Company Entity Shell Company Exercise Price Range [Axis] Exercise Price Range [Axis] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Financial Instrument [Axis] Financial Instrument [Axis] Subsequent Event Subsequent Event [Member] Document Period End Date Document Period End Date Range of Exercise Prices Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items] Archemix Archemix Corp [Member] Represents information pertaining to Archemix Corp. Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Unusual or Infrequent Item, or Both [Axis] Unusual or Infrequent Item, or Both [Axis] Total assets Assets Debt Disclosure [Abstract] Net loss per common share: Basic and diluted net loss per common share calculation: Earnings Per Share [Abstract] Income Statement Location [Axis] Income Statement Location [Axis] Antidilutive Securities [Axis] Antidilutive Securities [Axis] First Indication First Indication [Member] First Indication [Member] Balance at beginning of period (in shares) Balance at end of period (in shares) Shares, Issued Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Accounting Policies [Abstract] Accounting Policies [Abstract] Total interest expense related to 2022 Term Loan Facility Interest Expense, Debt Milestone Events [Axis] Milestone Events [Axis] Information pertaining to milestone events. Line of Credit Line of Credit [Member] Asset-backed securities Investments in asset-backed securities Asset-Backed Securities [Member] Prepaid expense and other assets Increase (Decrease) in Prepaid Expense and Other Current Assets The increase (decrease) during the reporting period in the value of prepaid expenses and other current assets not separately disclosed in the statement of cash flows. Loss before income tax benefit Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Stockholders' equity Stockholders' Equity Attributable to Parent [Abstract] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Net Income (Loss) Per Common Share Earnings Per Share [Text Block] Schedule of Weighted-average Assumptions Used to Estimate Grant Date Fair Value of Stock Options Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Gain on sale of IC100 & IC200 Gain (Loss) on Disposition of Intangible Assets Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Schedule of Components of Income Tax Benefit Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Award Type [Domain] Award Type [Domain] Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Number of warrants issued (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Remaining weighted average period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Proceeds from stock plans Proceeds from Stock Plans Auditor Information [Abstract] Auditor Information Financing Activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Entity Registrant Name Entity Registrant Name Issuance of common stock and pre-funded warrants, net (in shares) Stock Issued During Period, Shares, New Issues End term charges percentage Debt Instrument, End Term Charges Percentage Debt Instrument, End Term Charges Percentage Agreement Research and Development Arrangement, Contract to Perform for Others [Line Items] Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Exercise prices, high end of range (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Upper Range Limit Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Supranational securities Investments in supranational securities Supranational Securities [Member] Supranational Securities Entity Address, City or Town Entity Address, City or Town Employee Benefit Plan Retirement Benefits [Text Block] Leases [Abstract] Leases [Abstract] Maturity date no earlier than Long-Term Debt, Term Operating expenses: Operating Expenses [Abstract] Change in unrecognized tax liability Unrecognized Tax Benefits, Period Increase (Decrease) Basis of Consolidation Consolidation, Policy [Policy Text Block] Minimum Minimum [Member] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Entity Emerging Growth Company Entity Emerging Growth Company Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Auditor Name Auditor Name Fair Value Measurements Fair Value Disclosures [Text Block] Federal net operating loss carryforwards Operating Loss Carryforwards Trading Symbol Trading Symbol Entity File Number Entity File Number Research and development credit Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent Weighted Average Remaining Life (Years) Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term Qualified cash percent Debt Instrument, Covenant, Qualified Cash Waiver, Percent Debt Instrument, Covenant, Qualified Cash Waiver, Percent RSUs expected to vest (in shares) Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Expected To Vest The number of equity-based payment instruments, excluding stock (or unit) options, that are expected to vest in the future as of the reporting date. Research and development Research and Development Expense Gross amount of increases in unrecognized tax benefits during the period - prior year provisions Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Research, manufacturing and clinical equipment Equipment [Member] Title of Individual [Axis] Title of Individual [Axis] Awarded (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Effective income tax rate Effective Income Tax Rate Reconciliation, Percent Underwritten Offering, Underwriters Underwritten Offering, Underwriters [Member] Underwritten Offering, Underwriters Options outstanding (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Use of Estimates Use of Estimates, Policy [Policy Text Block] Investments in money market funds Cash and Cash Equivalents, Fair Value Disclosure Other comprehensive income Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Milestone Events [Domain] Milestone Events [Domain] Represents the types of milestone events. Gross amount of decreases in unrecognized tax benefits during the period - other Unrecognized Tax Benefits, Other Increase (Decrease) Unrecognized Tax Benefits, Other Increase (Decrease) The Wall Street Journal prime rate Prime Rate [Member] Increase in number of shares available under the Plan (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized 2019 Inducement Plan Two Thousand Nineteen Inducement Plan [Member] Two Thousand Nineteen Inducement Plan [Member] Achievement of Specified Commercial Milestones Achievement Of Specified Commercial Milestones [Member] Represents information pertaining to the achievement of specified commercial milestones. Shares issued for license fees (in shares) Shares Issued For License Fees Shares Issued For License Fees Accounts payable and accrued expenses Increase (Decrease) in Accounts Payable and Accrued Liabilities Income Taxes Income Tax Disclosure [Text Block] State Deferred State and Local Income Tax Expense (Benefit) Warrant price (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Interest expense paid in cash Interest Paid, Excluding Capitalized Interest, Operating Activities Basic (in dollars per share) Net loss per common share - basic (in dollars per share) Earnings Per Share, Basic Schedule of Commitments and Contingencies [Line Items] Schedule of Commitments and Contingencies [Line Items] Schedule of Commitments and Contingencies [Line Items] Proceeds from employee stock plan purchases and stock option exercises Proceeds From Stock Options And Warrants Exercised The cash inflow from associated with the amount received from holders exercising their stock options and warrants. This item inherently excludes any excess tax benefit, which the entity may have realized and reported separately. Total fair value vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Counterparty Name [Domain] Counterparty Name [Domain] Total stockholders' equity Balance at beginning of period Balance at beginning of period Stockholders' Equity Attributable to Parent Expired or forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Other Deferred Tax Assets, Other Entity Interactive Data Current Entity Interactive Data Current Shares issued (in shares) Sale of Stock, Number of Shares Issued in Transaction Schedule of Cash Proceeds From, and the Aggregate Intrinsic Value of, Stock Options Exercised Cash Proceeds Received and Tax Benefit from Share-Based Payment Awards [Table Text Block] License and technology payments Deferred Tax Assets License and Technology Payments Amount before allocation of valuation allowances of deferred tax asset attributable to deductible license and technology payments. Aggregate intrinsic value of RSUs expected to vest Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Expected To Vest Intrinsic value of equity-based compensation awards expected to vest. Excludes stock and unit options. Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Investments in money market funds Money Market Funds [Member] Accumulated Deficit Retained Earnings [Member] Unrecognized compensation costs Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Litigation Status [Domain] Litigation Status [Domain] Schedule of Commitments and Contingencies [Table] Schedule of Commitments and Contingencies [Table] Schedule of information pertaining to commitments and contingencies. Common Stock Common Stock [Member] Schedule of Share-based Compensation Expense Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Other comprehensive (loss) income Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Number of reporting segments Number of Reportable Segments Number of shares of common stock available for issuance under the Plan (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Class of Stock [Axis] Class of Stock [Axis] Summary of the Company's Outstanding Shares of RSU Awards Schedule of Nonvested Restricted Stock Units Activity [Table Text Block] Income Taxes Income Tax, Policy [Policy Text Block] Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards [Line Items] Statement [Table] Statement [Table] Purchase agreement consideration (in us dollar per share) Sale of Productive Assets, Consideration Received, Equity Interests Issued and Issuable, Par Value Sale of Productive Assets, Consideration Received, Equity Interests Issued and Issuable, Par Value Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Issuance of common stock in connection with private offering Stock Issued During Period, Value, Acquisitions Furniture and fixtures Furniture and Fixtures [Member] Current assets Assets, Current [Abstract] Lease liability, non-current Total long-term operating lease liabilities Operating Lease, Liability, Noncurrent Research and development credits Deferred Tax Assets, Tax Credit Carryforwards, Research Defined contribution plan, cost recognized Defined Contribution Plan, Cost Statistical Measurement [Axis] Statistical Measurement [Axis] Asset Acquisition [Domain] Asset Acquisition [Domain] $4.89-$8.07 Exercise Price Range Three [Member] Represents information pertaining to the exercise price range three. Accumulated deficit Retained Earnings (Accumulated Deficit) Cash equivalents Cash Equivalents, at Carrying Value Purchase of marketable securities Payments to Acquire Marketable Securities Equity Components [Axis] Equity Components [Axis] Public Stock Offering Public Stock Offering [Member] Public Stock Offering [Member] Recurring Basis Fair Value, Recurring [Member] Segment and geographic information Segment Reporting, Policy [Policy Text Block] Avacincaptad Pegol Avacincaptad Pegol [Member] Avacincaptad Pegol Licensing agreement term Licensing Agreement Term Licensing Agreement Term Interest income, net Interest Income (Expense), Nonoperating, Net Document Fiscal Year Focus Document Fiscal Year Focus Statement [Line Items] Statement [Line Items] Prepayment penalty prior first year Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs Prior To First Anniversary Of Closing Date Debt Instrument, Percentage Of Prepayment Penalty, Prepayment Occurs Prior To First Anniversary Of Closing Date Outstanding, beginning of period (in shares) Outstanding, end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Capitalized R&D Deferred Tax Assets, in Process Research and Development Variable Rate [Domain] Variable Rate [Domain] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Loss Contingencies [Table] Loss Contingencies [Table] Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Right-of-use assets, net Operating Lease, Right-of-Use Asset Accumulated Other Comprehensive Income (Loss) AOCI Attributable to Parent [Member] Series A Preferred Stock Series A Preferred Stock [Member] 2013 Plan Stock Incentive 2013 Plan [Member] Represents information pertaining to the 2013 Stock Incentive Plan. Auditor Firm ID Auditor Firm ID Contingent consideration Asset Acquisition, Contingent Consideration Arrangements, Range Of Outcomes, Value, High Asset Acquisition, Contingent Consideration Arrangements, Range Of Outcomes, Value, High Weighted-average exercise price of options (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Operating lease rent expense Operating Lease, Expense Document Transition Report Document Transition Report Local Phone Number Local Phone Number Wet AMD Wet AMD Product [Member] Wet AMD Product [Member] Patients in trial Number Of Patients In Trial Number Of Patients In Trial Summary of the Stock Option Activity Including Weighted Average Exercise Prices, Options Outstanding and Exercisable Share-Based Payment Arrangement, Option, Activity [Table Text Block] Loss from operations Operating Income (Loss) Amount to be paid on achievement of milestone Amount to be Paid On Achievement of Milestone Represents the amount to be paid by the entity on achievement of various milestones. Recently Adopted Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Litigation Status [Axis] Litigation Status [Axis] Share-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Achievement Of Specified Commercial Sales Milestones Achievement Of Specified Commercial Sales Milestones [Member] Achievement Of Specified Commercial Sales Milestones Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Axis] Adjustments to reconcile net loss to net cash (used in) provided by operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Income tax benefit Income tax benefit Income tax benefit Income Tax Expense (Benefit) Sales Milestone Payments Additional Sales Milestone Payments [Member] Additional Sales Milestone Payments Valuation allowance Deferred Tax Assets, Valuation Allowance Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] Series B Preferred Stock Series B Preferred Stock [Member] Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Income Statement [Abstract] Income Statement [Abstract] Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Entity Public Float Entity Public Float Federal Deferred Federal Income Tax Expense (Benefit) Additional paid-in capital Additional Paid-in Capital [Member] Document Fiscal Period Focus Document Fiscal Period Focus Options Outstanding Share Based Compensation, Shares Authorized under Stock Option Plans Exercise Price Range Options Outstanding [Abstract] Employees Employees [Member] Represents information pertaining to the employees. Milestone 3 is achieved Tranche Four [Member] Tranche Four Aggregate intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Milestone 1 is achieved through December 15, 2022 Tranche Two [Member] Tranche Two Diluted (in shares) Weighted average common shares outstanding - dilutive (in shares) Weighted Average Number of Shares Outstanding, Diluted Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Expected term of options (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Loss Contingencies [Line Items] Loss Contingencies [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Contingently issuable shares, asset acquisition (in shares) Asset Acquisition, Contingent Consideration Arrangements, Range Of Outcomes, Shares Issuable, High Asset Acquisition, Contingent Consideration Arrangements, Range Of Outcomes, Shares Issuable, High ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Debt issuance costs Debt Issuance Costs, Gross Accounts payable and accrued expenses Accounts Payable and Accrued Liabilities, Current miniCEP290 miniCEP290 [Member] miniCEP290 [Member] Common stock—0.001 par value, 200,000,000 shares authorized, 136,639,687 and 115,277,012 shares issued and outstanding at December 31, 2022 and December 31, 2021, respectively Common Stock, Value, Issued Trial data period Trial Data Period Trial Data Period Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Series Seed Preferred Stock Series Seed Preferred Stock Member [Member] Series Seed Preferred Stock Member Awarded (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Schedule of Potentially Dilutive Securities Excluded from the Computations of Diluted Weighted Average Common Shares Outstanding Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Private Placement Private Placement [Member] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Beginning of period End of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Lenders option to invest in equity financing Debt Instrument, Lenders Option To Invest In Equity Financing Debt Instrument, Lenders Option To Invest In Equity Financing Inception 4 Inception 4 [Member] Inception 4 [Member] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Current liabilities Liabilities, Current [Abstract] Cash proceeds from options exercised Proceeds from Stock Options Exercised Proceeds from term loan Proceeds from Issuance of Long-Term Debt Common stock, shares issued (in shares) Common Stock, Shares, Issued Weighted-average remaining contractual life of options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Cash, cash equivalents and available for sale securities Cash And Cash Equivalents And Debt Securities Available For Sale Cash And Cash Equivalents And Debt Securities Available For Sale License Agreements License Agreement Terms [Member] Income Statement Location [Domain] Income Statement Location [Domain] Fair Value Measurements Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Concentration of Suppliers Concentration of Suppliers Policy, [Policy Text Block] Disclosure of accounting policy for concentration of suppliers. Amendment Flag Amendment Flag Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Covenant revenue from sale, maintained market capitalization Debt Instrument, Covenant, Revenue From Sale, Market Capitalization Maintained, Waiver Debt Instrument, Covenant, Revenue From Sale, Market Capitalization Maintained, Waiver Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Entity Current Reporting Status Entity Current Reporting Status Other assets Other Assets, Noncurrent Options exercisable at end of year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Contingent development and regulatory milestone amount Sale of Productive Assets, Contingent Consideration Arrangements, Range of Outcomes, Value, High Sale of Productive Assets, Contingent Consideration Arrangements, Range of Outcomes, Value, High Purchase price of common stock as percentage of fair market value Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent University Of Massachusetts (UMass) University Of Massachusetts (UMass) [Member] University Of Massachusetts (UMass) [Member] U.S. federal statutory income tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Counterparty Name [Axis] Counterparty Name [Axis] Outstanding at beginning of year (in shares) Outstanding at end of year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Schedule of Interest Expense Interest Income and Interest Expense Disclosure [Table Text Block] Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code State taxes, net of federal 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Security Exchange Name Security Exchange Name Outstanding at beginning of year (in dollars per share) Outstanding at end of year (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Preferred stock—$0.001 par value, 5,000,000 shares authorized, no shares issued or outstanding Preferred Stock, Value, Issued Underwritten Offering Underwritten Offering [Member] Underwritten Offering Withholding period Offering period Share-Based Compensation Arrangements By Share-based Payment Award, Withholding Period Share-Based Compensation Arrangements By Share-based Payment Award, Withholding Period Issuance of common stock under employee stock compensation plans Stock Issued During Period, Value, Issued for Services Restricted stock units Restricted Stock [Member] Specified Commercial Sales Milestones Related to a Licensed Product Specified Commercial Sales Milestones Related to a Licensed Product [Member] Specified Commercial Sales Milestones Related to a Licensed Product [Member] Property and equipment Property and Equipment Property, Plant and Equipment [Line Items] Schedule of Debt Schedule of Debt [Table Text Block] General and administrative General and Administrative Expense [Member] Opus Genetics Inc Opus Genetics Inc. [Member] Opus Genetics Inc. 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